The Power of Nutrition
in Curing Cancer
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Main Article
január 14, 2025
The Power of Nutrition in Curing Cancer
Cancer pathomechanism
Peter Grandics
A-D Research Foundation, 5922 Farnsworth Ct, Carlsbad, CA 92008, USA
A-D Research Foundation is committed to:
- Developing a new understanding of the patho-mechanism of cancer
- Developing new, breakthrough therapies by utilizing this knowledge
Currently held views on cancer mechanism
Main Emphasis on Genetics:
- From a single cell that loses its differentiated state through sequential mutations
- Initiation-promotion-progression concept explains the steps in a sequential process
- Oncogenic theories suggests that defects in tumor suppressor genes cause malignancy
The cancer stem cell concept
- Cancer may develop out of a single cell
- Just a small fraction of tumor cells have the ability of disease propagation
- Cancer stem cells could be mutated normal stem cells
- Cancer stem cells may develop from other cell types
Observations & Analysis
- Body mounts a low intensity immune response to cancer
- Immunosuppressive cytotoxic antineoplastic therapies may cause regression of a clinically established cancer
- Immunosuppression that can be lethal in a fungal infection may benefit cancer suppression
- Autoimmunity is also controlled by immunosuppression
- Cancer cells “attack self” comparably to autoreactive T cells
- Could there be a relationship between autoimmunity and cancer?
- Could the cancer stem cell arise from damaged autoreactive
- T cells?
Comparison of inflammatory cells and cancer cells
Inflammatory T cells:
- Inflammatory cytokine secretion
- Attachment to neutrophils, macrophages, endothelium
- Cause platelet aggregation
- Secrete tissue factor
- Induce clotting
- Temporary wound stroma development
Cancer cells:
All the same except that the wound stroma is permanent (tumor)
Infection, inflammation & cancer
- Microbial antigens are present in the patient’s sera
- Pathogen eradicating therapy led to the regression of some cancers
- Hit-and-stay pathogens distort the immune response using the TLR signaling system
- Th2, Treg dominance established
- Th2 cytokines antagonize cellular immune response
- Tumor cells secrete Th2 polarizing cytokines that inhibit tumor specific cytotoxic T cells
Infection, autoimmunity & cancer
- A number of pathogens are linked to autoimmunity & cancer
- Antinuclear antibodies (ANA) were found in the sera of 19% of patients
- Autoantibodies are observed against tissue-specific antigens, nucleoproteins, membrane receptors, proliferation-associated antigens, tissue-restricted antigens,
- About 60% of cancers express anti-p53 autoAbs
- Infections may induce autoimmune serological features without overt autoimmune disease or organ involvement
- Cancer patients exhibit a higher percentage of autoreactive T cells
- Mechanism of autoimmunity via molecular mimicry
References
You can find more information here:
https://cure4cancer.me/wp-content/uploads/2024/12/cancer-pathomechanism.pdf